LRRK2 G2385R and R1628P mutations are associated with an increased risk of Parkinson's disease in the Malaysian population.

Biomed Res Int · 2014 · PMC4163406 · PMID 25243190

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

a trend towards significanceP = 0.054so close (0.05 < p ≤ 0.1)

The G2385R variant was associated with PD, with an odds ratio (OR) of 2.22 ( P = 0.019), while the R1628P variant had an OR of 1.23 with a trend towards significance ( P = 0.054).

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showed a trendno p-value reported

We found that G2385R was significantly associated with PD and R1628P showed a trend towards being a risk factor. 2.

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