2a ): a statistically significant ( P = 0.04) reduction of inflammatory cells was observed in mice treated with the 1.25- or 2.5-μg doses; there was also a tendency towards decreased cell inifiltration in the mice treated with the 0.25-μg dose, but this did not reach statistical significance (Fig. 2b ).
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Treatment with recombinant interferon-beta reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis.
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