Experiments for contrast analysis To explore the two different scenarios considered above (highly significant local differences between groups, and more subtle wide spread differences) numerical experiments have been devised.
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Coordinate based meta-analysis of functional neuroimaging data using activation likelihood estimation; full width half max and group comparisons.
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Table 1 shows that the results of contrast meta-analysis are not significant (FCDR>0.05) for 10 or 14 studies per group, and just about significant with 16 studies per group.