Barely Significant
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Hypoxic preconditioning protection is eliminated in HIF-1α knockout mice subjected to neonatal hypoxia-ischemia.

Pediatr Res · 2014 · PMC4167022 · PMID 24713818

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showed a trendp=0.08so close (0.05 < p ≤ 0.1)
Spectrin 120 was not significantly changed in either wildtype or HIF-1α knockout after HI, but the HIF-1α knockout cortex showed a trend toward more spectrin 120 than wildtype at 24 h ( Figure 5b , p=0.08).

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