Diabetes mellitus and risk of age-related macular degeneration: a systematic review and meta-analysis.

PLoS One · 2014 · PMC4169602 · PMID 25238063

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closest p

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of borderline significanceno p-value reported

In addition, in the subgroup analysis of case-control studies, an association of borderline significance between diabetes and AMD (OR, 1.23; 95% CI, 0.97–1.56) was presented if the study by Nitsch et al [13] was excluded.

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of marginal significanceno p-value reported

When removing the studies conducted by Shalev et al and Hahn et al in the subgroup analysis of cohort studies, respectively, although the p values for diabetes and AMD became insignificant, the direction of ORs was kept and associations of marginal significance were revealed (removing study by Shalev et al: OR, 1.04; 95% CI, 0.99–1.10; Hahn et al: OR, 1.12; 95% CI, 0.98–1.29).

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