Reduction in CD4 central memory T-cell subset in costimulation modulator abatacept-treated patients with recent-onset type 1 diabetes is associated with slower C-peptide decline.

Diabetes · 2014 · PMC4171657 · PMID 24834977

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a nonsignificant trendno p-value reported

Abatacept also induced a decline in the number of circulating CD4 + CD25 high cells, and we observed a nonsignificant trend for this change to associate with C-peptide level decline.

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failed to reach statistical significanceno p-value reported

Similar findings to those described above for CM, naive, and Treg CD4 T cells were made when absolute counts of these subpopulations were analyzed, but these failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.