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Circulating Type-1 Anti-Tumor CD4(+) T Cells are Preferentially Pro-Apoptotic in Cancer Patients.

Front Oncol · 2014 · PMC4178427 · PMID 25325015

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Furthermore, we identified a trend for increased frequencies of TAA- (but not FluM1-) specific CD4 + T cells as a function of disease stage, although this did not reach statistical significance (Figure 3 and data not shown).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.