Effects of isoxazolo-pyridinone 7e, a potent activator of the Nurr1 signaling pathway, on experimental autoimmune encephalomyelitis in mice.

PLoS One · 2014 · PMC4181297 · PMID 25265488

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closest p · 1.8× alpha

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showed a trendP = 0.09so close (0.05 < p ≤ 0.1)

2E ; Student's t -test, ** P <0.01), while demyelination was not significantly reduced, even if it showed a trend to decrease in IP7e-treated EAE mice ( Fig. 2F ; Student's t -test, P = 0.09).

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