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A random set scoring model for prioritization of disease candidate genes using protein complexes and data-mining of GeneRIF, OMIM and PubMed records.

BMC Bioinformatics · 2014 · PMC4181406 · PMID 25253562

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a strong trendno p-value reported
Particularly, those disease genes which are also essential genes show a strong trend to encode hub proteins [ 28 ].

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