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Non-neural tyrosine hydroxylase, via modulation of endocrine pancreatic precursors, is required for normal development of beta cells in the mouse pancreas.

Diabetologia · 2014 · PMC4181516 · PMID 25082160

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A similar trend was observed for Nkx2.2 mRNA levels, although the differences between the Th +/+ and Th − / − groups did not reach statistical significance (Fig. 4e ).

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