Functional Relationship between Tumor-Associated Macrophages and Macrophage Colony-Stimulating Factor as Contributors to Cancer Progression.

Front Immunol · 2014 · PMC4188035 · PMID 25339957

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Indeed, when patients were substratified in subsets, the M-CSF response signature was associated with poor prognosis among low-grade tumors and showed a trend for an association with improved prognosis among estrogen-receptor-negative tumors and among tumors with a TP53 mutation gene-expression signature ( 68 ).

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