Translating the immunogenicity of prime-boost immunization with ChAd63 and MVA ME-TRAP from malaria naive to malaria-endemic populations.

Mol Ther · 2014 · PMC4188556 · PMID 24930599

Europe PMC DOI

hedged sentences

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closest p · 1.4× alpha

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boldest claim

The sentences

highly significantP < 0.000not a probability at all

After boosting with MVA, a highly significant relationship between T-cell responses measured postprime and postboost was apparent (Spearman's r = 0.6, P < 0.000 1, Figure 3h ).

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showed a trendP = 0.07so close (0.05 < p ≤ 0.1)

Within individual trial sites, increases were not statistically significant, however when data across trials were combined, increases in the magnitude of CD4 + IFN-γ + and CD4 + TNFα + populations reached significance ( P = 0.007 and P = 0.009, Kruskall-Wallis test with Dunn's multiple comparison) and the increase in CD4 + IL2-secreting cells showed a trend toward an increase after vaccination ( P = 0.07).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.