The total numbers of IgG ASCs were similar between BALB/c and C57BL/6 mice ( Figure 1 b, upper panel) When Env-specific (total gp140-F-specific) ASCs were measured we observed a higher absolute number of antigen-specific cells in BALB/c (mean 2.4 × 10 6 cells) compared to C57BL/6 mice (mean 1.6 × 10 6 cells), consistent with the ELISA results, although the difference did not reach statistical significance ( p = 0.09).
1
0.0900
0.0900