Blood vessel repair and regeneration in the ischaemic heart.

Open Heart · 2014 · PMC4189230 · PMID 25332783

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showed a trendno p-value reported

In the Angiogenic GENe Therapy (AGENT) double-blind RCT, the administration of five increasing doses of Ad5-FGF4 in patients with stable angina pectoris showed a trend towards clinical improvement in exercise tolerance.

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an encouraging trendno p-value reported

The AGENT 2 study showed an encouraging trend for improved myocardial perfusion in treated patients compared with the placebo group, 39 whereas the results of the AGENT 3 and AGENT 4 trials showed no significant differences between treatment and placebo in angina symptoms, angina class or exercise tolerance.

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