Capecitabine-induced cardiotoxicity: more evidence or clinical approaches to protect the patients' heart?

A retrospective study showed that cardiotoxicity was more frequently reported in patients receiving capecitabine plus taxanes than in those treated with capecitabine single agent (3.7% versus 1.9%), although the difference did not reach statistical significance. 38 In our patient, cardiac toxicity was evident both in the TX schedule and in association with lapatinib.

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