Clinical Trials Express: fracture risk reduction with denosumab in Japanese postmenopausal women and men with osteoporosis: denosumab fracture intervention randomized placebo controlled trial (DIRECT).

The incidence of new or worsening vertebral and new vertebral fracture in older men in the denosumab group was lower than that in the placebo group, although the difference in these incidences did not reach statistical significance, possibly due to the small sample size ( Figure 2 ).

also in 111,027 other papers