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Gli1 haploinsufficiency leads to decreased bone mass with an uncoupling of bone metabolism in adult mice.

PLoS One · 2014 · PMC4196929 · PMID 25313900

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showed a trendno p-value reported
Consistent with this finding, the Gli1 +/− mice showed a trend toward increased bone resorption capacity parameters, compared to WT mice ( Figure 2D , see ES/BS and Oc.S/BS).

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