Barely Significant
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Serum endostatin levels are elevated in colorectal cancer and correlate with invasion and systemic inflammatory markers.

Br J Cancer · 2014 · PMC4200096 · PMID 25137019

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showed a trendP =0.055so close (0.05 < p ≤ 0.1)
Our results also showed a trend towards elevated serum endostatin levels in the presence of deeper local invasion of the tumour (T classification) in univariate analysis ( Table 3 ; P =0.055) and significant correlation between higher serum endostatin levels and the invasion of the cancer tissue through the muscularis propria (T1-2 vs T3-4) in univariate ( Table 3 ; P =0.007) and multivariate analysis ( Table 7 ; P =0.032).

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