Expression and DNA methylation of TNF, IFNG and FOXP3 in colorectal cancer and their prognostic significance.

Br J Cancer · 2014 · PMC4200101 · PMID 25225903

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significanceP =0.06so close (0.05 < p ≤ 0.1)

FOXP3 expression in tumours was found to be high in stage 3 tumours, however, the enhanced expression approached but did not reach statistical significance ( P =0.06).

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highly significantno p-value reported

Heriot et al (2000) have shown a highly significant reduction in production of TNF- α and IFN- γ (interferon- γ ) by lipopolysachharide (LPS) stimulated whole-blood cultures derived from patients with CRC as compared to similarly aged controls.

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