Insulin resistance is associated with MCP1-mediated macrophage accumulation in skeletal muscle in mice and humans.

PLoS One · 2014 · PMC4206428 · PMID 25337938

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a clear trendno p-value reported

Nevertheless, obese subjects presented a clear trend towards higher insulinemia and HOMA-IR, which was indicative of an insulin resistance state of this population.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.