As expected, the percentage of Lin - Sca-1 + c-Kit + (LSK) cells showed a decrease in AMD3100-treated OVX mice, compared with PBS-treated OVX mice in BM, although this did not reach statistical significance ( Fig. 2 B).
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AMD3100 improves ovariectomy-induced osteoporosis in mice by facilitating mobilization of hematopoietic stem/progenitor cells.
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