iAUC for GIP (2,613 ± 101, 2,611 ± 193, 2,301 ± 229 pmol ⋅ L −1 ⋅ h, P = 0.45) was not different among NGT, IGT, and T2D, whereas iAUC for GLP-1 (183.4 ± 25.3, 139.4 ± 48.1, 461.1 ± 57.1 pmol ⋅ L −1 ⋅ h, P = 0.08) and PP (510 ± 44, 597 ± 83, 752 ± 99 pmol · L −1 ⋅ h, P = 0.07) showed a trend.
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β-cell function, incretin effect, and incretin hormones in obese youth along the span of glucose tolerance from normal to prediabetes to type 2 diabetes.
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