CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells.

A moderate correlation was also seen between the frequencies of resting CD4 + T cells containing HIV DNA by ddPCR and either the expression of PD-1 or all markers (CD38 + HLA-DR + CCR5 + PD1 + ) on CD8+ T cells (PD-1: ρ = 0.45, P = 0.08; All: ρ = 0.46, P = 0.08) ( Figure 1 ) although it did not reach statistical significance.

also in 111,027 other papers