Differential effects of glyoxalase 1 overexpression on diabetic atherosclerosis and renal dysfunction in streptozotocin-treated, apolipoprotein E-deficient mice.

As is seen in Figure 2 A, mice showed little atherosclerosis in the aortic root and, while GLO1TG Apoe −/− mice and non‐TG Apoe −/− littermates that had been administered STZ, showed a trend toward increased lesion area compared to vehicle‐treated mice, this did not achieve statistical significance ( P < 0.1).

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