Subchondral bone influences chondrogenic differentiation and collagen production of human bone marrow-derived mesenchymal stem cells and articular chondrocytes.

Arthritis Res Ther · 2014 · PMC4209060 · PMID 25296561

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In contrast, OAB-cocultured chondrocytes showed a trend to increased Young’s modulus (depending on strain applied), while hydraulic permeability and aggregate modulus also remained unchanged by subchondral bone coculture.

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