highly significantP <0.001
The following variables that showed a highly significant statistical difference ( P <0.001) in the univariate analyses were entered a stepwise backward logistic regression model: age; Euroscore; preoperative plasma creatinine level; ScO2 minox ; type of surgery; duration of surgery; duration of cardiopulmonary bypass (CPB); lowest hematocrit during CPB; intra- and postoperative use of inotropic/vasoactive agents (noradrenaline, dobutamine, vasopressine); cumulative use of blood products; mean RPP within the first 8 hours after ICU admission, time to first extubation (hours), and reintubation.