Classical and Alternative Activation and Metalloproteinase Expression Occurs in Foam Cell Macrophages in Male and Female ApoE Null Mice in the Absence of T and B Lymphocytes.

Plaque size, composition, M1/M2 markers, and MMP protein expression in FCMs in atherosclerotic plaques from ApoE KO and DKO mice Plaques in the aortic sinus tended to be smaller in DKO compared with ApoE KO mice but this did not reach statistical significance (Figure 6 A).

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