How innovative are new drugs launched in the UK? A retrospective study of new drugs listed in the British National Formulary (BNF) 2001-2012.

BMJ Open · 2014 · PMC4212185 · PMID 25344485

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a negative trendno p-value reported

However, studies published in the last decade that define innovativeness on the basis of therapeutic value all report a negative trend in the innovativeness of new drugs, despite using different approaches to measurement and reporting time periods varying from 1990–2003 to 2001–2010.

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