Collectively, the Vglut2-cKO mice group displayed a trend for more variable circadian rhythmicity than the control group in DD conditions although differences in amplitude variance of the wheel-running rhythm did not reach statistical significance ( Figures 2D–E ).
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Mice deficient of glutamatergic signaling from intrinsically photosensitive retinal ganglion cells exhibit abnormal circadian photoentrainment.
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