Impact of preprocedural mitral regurgitation upon mortality after transcatheter aortic valve implantation (TAVI) for severe aortic stenosis.

While those with moderate–severe MR had higher 12 m mortality (30.2% vs 21.2%), it did not reach statistical significance (p=0.068). 15 Improvement in the degree of MR after TAVI has been associated with the absence of pulmonary hypertension and atrial fibrillation, 8 12 mean aortic valve gradient >40 mm Hg 8 and functional MR. 8 12 Similarly after sAVR functional MR has been associated with improvement in the severity of MR. 4 Functional MR relies on an incompetent orifice and sufficient systolic gradient between the LV and left atrium.

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