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Deregulation of serum microRNA expression is associated with cigarette smoking and lung cancer.

Biomed Res Int · 2014 · PMC4217347 · PMID 25386559

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an increasing trendno p-value reported
A correlation analysis showed a negative correlation between the smoking index and the serum levels of let-7i-3p and miR-154-5p and that an increasing trend in the smoking index is associated with lower relative expression of let-7i-3p and miR-154-5p.

also in 63,971 other papers

showed a trendno p-value reported
The serum miRNA expression profiles of lung-cancer patients showed a trend similar to that in smokers.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.