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Hydroxychloroquine in patients with inflammatory and erosive osteoarthritis of the hands (OA TREAT): study protocol for a randomized controlled trial.

Trials · 2014 · PMC4219005 · PMID 25348033

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showed a trendno p-value reported
Although clinical trials showed a trend for a good efficacy of HCQ in hand OA, the development of the drug was not pursued further.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.