Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.

Hum Mol Genet · 2014 · PMC4222357 · PMID 24973356

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

nearly statistically significantP = 6.47 × 10 −05actually significant

A single marker in FGF20 becomes nearly statistically significant ( P = 6.47 × 10 −05 ) when using only pathologically confirmed DLB cases.

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highly significantno p-value reported

Firstly, the association remains highly significant when we restrict the analysis to neuropathologically diagnosed DLB cases; and second, if a contamination with AD cases were to have occurred, we would expect to see associations with the other reported GWAS hits in AD.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.