Evolution of extensively drug-resistant Mycobacterium tuberculosis from a susceptible ancestor in a single patient.

Genome Biol · 2014 · PMC4223161 · PMID 25418686

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a clear trendno p-value reported

Intriguingly, isolates harboring the same resistance mutations also differed in growth efficiency in the presence of INH and STR, with a clear trend of increasing fitness (Figure 3 ).

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