Sensitive real-time PCR detection of pathogenic Leptospira spp. and a comparison of nucleic acid amplification methods for the diagnosis of leptospirosis.

PLoS One · 2014 · PMC4224423 · PMID 25379890

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0.1300

closest p · 2.6× alpha

0.1300

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did not reach statistical significancep = 0.13not close (p > 0.1)

The differences in rates of Leptospira detection using the reference 16S rtPCR (38.1%) and prior results using PCRs for flaB and lipL41 (16/65 samples detected, 25.4%) did not reach statistical significance (p = 0.13).

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