Characterization of natural polymorphic sites of the HIV-1 integrase before the introduction of HIV-1 integrase inhibitors in Germany.

J Int AIDS Soc · 2014 · PMC4225247 · PMID 25397491

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a significant trendno p-value reported

Results Overall, 56.8% (158/278) amino acid positions were polymorphic and 15.8% (25/158) of these positions exhibited a significant trend in amino acid variation over time.

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