Of the subjects who changed in vitamin D status from deficient to either insufficient or sufficient at 1 year into the trial, there was a trend towards response to atorvastatin treatment in 3-year CIMT progression, but this did not reach statistical significance.
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Vitamin D status is a determinant of atorvastatin effect on carotid intima medial thickening progression rate in children with lupus: an Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE) substudy.
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