Barely Significant
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Methylphenidate for attention deficit hyperactivity disorder and drug relapse in criminal offenders with substance dependence: a 24-week randomized placebo-controlled trial.

Addiction · 2014 · PMC4226329 · PMID 24118269

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showed a trendno p-value reported
However, in the MPH group, heart rate from baseline showed a trend to increase.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.