EPIQ-efficient detection of SNP-SNP epistatic interactions for quantitative traits.

Bioinformatics · 2014 · PMC4229902 · PMID 24931983

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near-significantP = 2.2 × 10 −13actually significant

Applying our method to a dataset from the Ludwigshafen risk and cardiovascular health study, we discovered a pair of SNPs with a near-significant interaction ( P = 2.2 × 10 −13 ), in only 1.5 h on 10 processors.

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