The role of high cell density in the promotion of neuroendocrine transdifferentiation of prostate cancer cells.

There was a slight trend towards an inverse correlation between Ki-67 score and γ-enolase expression (p = 0.146), suggesting that tumors with slower proliferation (Ki-67 low) have higher expression of the NED marker γ-enolase (Additional file 5 : Figure S4).

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Detection of mRNA levels of selected NED markers showed a trend of increased expression of TUBB3 (118%) and CHGA (117%) (Figure 4 G).

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