Influenza vaccine effectiveness in preventing influenza A(H3N2)-related hospitalizations in adults targeted for vaccination by type of vaccine: a hospital-based test-negative study, 2011-2012 A(H3N2) predominant influenza season, Valencia, Spain.

The mean (standard deviation) number of days from vaccination to onset of symptoms for influenza-positive subjects was 119 (21) compared with 109 (32) for influenza-negative subjects, with a significant trend for increasing risk ( P <0.0001) of a positive influenza result in the unadjusted analysis considering days elapsed since vaccination to onset of symptoms ( Table 4 ).

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