A field guide to whole-genome sequencing, assembly and annotation.

Evol Appl · 2014 · PMC4231593 · PMID 25553065

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a clear trendno p-value reported

Judging from recently completed whole-genome sequencing projects (Table 1 ), there is a clear trend moving away from traditional Sanger sequencing (∼1 kb sequence reads) and Roche 454 sequencing (up to 800 bp) towards short read technologies such as Illumina HiSeq (at present typically 150 bp) and SOLiD (typically 50 bp).

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