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The transcription factor ATOH8 is regulated by erythropoietic activity and regulates HAMP transcription and cellular pSMAD1,5,8 levels.

Br J Haematol · 2014 · PMC4232863 · PMID 24236640

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Serum iron levels generally tracked liver Atoh8 levels (Fig 5 B) although some of the treatments did not reach statistical significance (EPO treatment and EPO with carboplatin).

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