Treatment with pirfenidone for two years decreases fibrosis, cytokine levels and enhances CB2 gene expression in patients with chronic hepatitis C.

BMC Gastroenterol · 2014 · PMC4236537 · PMID 25064094

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showed a trendno p-value reported

TGF-β1, the emblematic pro-fibrogenic cytokine showed a trend to diminish in 67% of patients as seen in Figure 2 C.

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