The OPTIMIST-A trial: evaluation of minimally-invasive surfactant therapy in preterm infants 25-28 weeks gestation.

BMC Pediatr · 2014 · PMC4236682 · PMID 25164872

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a strong trendno p-value reported

Need for intubation <72 hrs was diminished after MIST, most notably for infants at 25–28 weeks gestation (OR 0.21, 95% CI 0.083-0.55), but with a strong trend in the same direction in the 29–32 week group (odds ratio 0.34, 95% CI 0.11-1.06).

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