Differential dermal expression of CCL17 and CCL18 in tuberculoid and lepromatous leprosy.

Both CCL17 ( Figure 1A ) and CCL18 ( Figure 1B ) expression were highly significant when analyzed in rank order based on Ridley-Jopling classification (non-parametric trend test, P = 1.5×10 −5 and 3.0×10 −8 , respectively).

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Patients with lepromatous leprosy had a non-significant trend (p = 0.16) of decreasing CCL17 levels ( Figure 5A ) and a significant trend (p = 0.036) of increasing CCL18 ( Figure 5B ) levels in the serum.

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However, all of these failed to reach significance when adjusted for multiple comparisons.

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