Analyses with paired t-tests showed significant improvements between visit 1&3 (43.10±20.52 vs 29.52±8.64; p = 0.014) and visits 2&3 (36.90±14.35 vs 29.52±8.64; p = 0.019), but not between visits 1&2 (p = 0.269) The mean levodopa ON-duration time increased by about 56 minutes at week 6 (visit 2) and 38 minutes at week 12 (visit 3) post eradication but these did not reach statistical significance when analysed using ANOVA (p = 0.06).
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Eradication of Helicobacter pylori infection improves levodopa action, clinical symptoms and quality of life in patients with Parkinson's disease.
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