Oxidative stress and respiratory system: pharmacological and clinical reappraisal of N-acetylcysteine.

COPD · 2014 · PMC4245155 · PMID 24787454

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highly significantno p-value reported

In the study by Stav et al ., treatment with NAC 1200 mg/day for 6 weeks significantly increased exercise time compared with placebo, with treatment differences of 22 s, which was highly significant ( 63 ).

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did not reach statistical significanceno p-value reported

This trend did not reach statistical significance, likely due to the relatively small number of patients enrolled in the study.

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