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Internalization and TLR-dependent type I interferon production by monocytes in response to Toxoplasma gondii.

Immunol Cell Biol · 2014 · PMC4245188 · PMID 25155465

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Moreover, production of IFN-β by Ly6-B2 + cells isolated from TLR4 KO or from TLR2x4 double KO mice was reduced to near the levels of the uninfected control samples, whereas loss of TLR2 led to a more modest reduction that did not reach statistical significance ( Fig. 1E ).

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