Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network.

However, multiple known associations with TSH levels in European ancestry were nominally significant in African Americans, including PDE8B (rs2046045 p = 0.03, β = −0.09), VEGFA (rs11755845 p = 0.01, β = −0.13), and NFIA (rs334699 p = 1.50×10 −3 , β = −0.17).

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In the European Americans, adjusting for BMI did not appreciably modify the results, though the results in both PDE8B and FOXE1 were more highly significant ( Table S7 ).

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